Transversus Abdominis Plane Blocks With and Without Dexamethasone: A Randomized Clinical Trial in Minimally Invasive Colorectal Surgery
Status: Recruiting
Location: See location...
Intervention Type: Drug
Study Type: Interventional
Study Phase: Phase 1/Phase 2
SUMMARY
Dexamethasone will be used as an adjunct to local anesthetics (bupivacaine) to prolong the duration of laparoscopically-placed transversus-abdominis plane blocks in elective colorectal resection.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: t
View:
• age \> 18
• ASA class I-III
• elective or urgent inpatient laparoscopic/laparoscopic assisted colorectal surgery.
Locations
Other Locations
Canada
Royal University Hospital
RECRUITING
Saskatoon
Contact Information
Primary
David N Ginther, MD
n.ginther@usask.ca
306-655-6893
Time Frame
Start Date: 2022-09-01
Estimated Completion Date: 2024-08-31
Participants
Target number of participants: 60
Treatments
Experimental: Dexamethasone
Dexamethasone 16mg will be added to local anesthetic solution for TAP blocks. 4mg will be injected at 4 anterior abdominal wall sites in a laparoscopically-administered TAP block. This is a single intraoperative dose.
No_intervention: Local anesthetic only
Local anesthetic (bupivacaine 0.25) 1mL/kg will be used for TAP blocks.
Related Therapeutic Areas
Sponsors
Leads: University of Saskatchewan